Zoetis – Vetscan Feline FeLV/FIV Rapid Test – Box of 10

INTENDED USE The VetScan Feline Leukemia Virus Antigen-Feline Immunodeficiency Virus Antibody (FeLV-FIV Combo)
Rapid Test is a visual rapid test for the qualitative detection of Feline Leukemia Virus antigen and Feline
Immunodeficiency Virus antibody in feline whole blood, serum, or plasma. This test is for veterinary use only.
FIV and FeLV are two of the most commonly diagnosed causes of disease and death in domestic cats (2,3).
Feline leukemia virus (FeLV) is a highly contagious retrovirus that can severely compromise a cat’s immune
system and predisposes cats to various diseases (1,2).
Transmission occurs from cat to cat via body fluids during casual contact or fighting. Identification of infected
cats helps prevent the spread of FeLV. Rapid diagnosis of FeLV infection is generally performed by detecting
viral antigen p27 from the core protein, which is found in high level in viremic cats. (1,2) Feline immunodeficiency
virus (FIV) is a lentivirus with world-wide distribution (4). Similarly to FeLV, FIV is transmitted mainly by saliva. FIV
infection has a long latent phase and therefore infected cats remain free of clinical signs for several years. Most
clinical signs and symptoms are not caused by FIV, but are the consequences of the immunodeficiency that FIV
induces (5). Typical manifestations are lymphadenopathy, weight loss, renal failure and chronic rhinitis (5).
The VetScan Feline Leukemia Virus Antigen-Feline Immunodeficiency Virus Antibody (FeLV-FIV Combo)
Rapid Test is based on the use of FeLV-specific antibodies and an FIV antigen in its respective immunochromatographic sandwich assay. For the FeLV strip, antibody-coated colloidal gold particles bind to FeLV
antigen in the sample. The bound antigen flows through the strip and is then captured by antibodies on the test
strip. For the FIV strip, antigen-coated colloidal gold particles bind to FIV antibody in the sample. The bound
antibodies flow through the strip and are then captured by antigen on the test strip. The accumulation of the
captured gold particle/antigen or antibody complex causes a color to become visible in the Test (T) area. To serve
as a procedural control, a colored line in the Control line (C) area will always appear regardless if the sample is
positive or negative.