Zoetis – Comprehensive Diagnostic Profile

1. Intended Use

The VetScan® Comprehensive Diagnostic Profile reagent rotor used with the VetScan Chemistry Analyzer utilizes dry and liquid reagents to provide in vitro quantitative determinations of alanine aminotransferase (ALT), albumin (ALB), alkaline phosphatase (ALP), amylase (AMY) total calcium (CA++), creatinine (CRE), globulin* (GLOB), glucose (GLU), phosphorus (PHOS), potassium (K+), sodium (NA+), total bilirubin (TBIL), total protein (TP), and urea nitrogen (BUN) in heparinized whole blood, heparinized plasma, or serum.

* Calculated Value

2. Summary and Explanation of Tests

The VetScan Comprehensive Diagnostic Profile reagent rotor and the VetScan Chemistry Analyzer comprise an in vitro diagnostic system that aids the veterinarian in diagnosing the following disorders:

Alanine aminotransferase: Liver diseases, including viral hepatitis and cirrhosis; heart diseases.

Liver diseases, including viral hepatitis and cirrhosis; heart diseases.

Albumin: Liver and kidney diseases.
Alkaline phosphatase: Liver, bone, parathyroid, and intestinal diseases.

Amylase: Kidney and pancreatic disease.
Calcium: Parathyroid, bone and chronic renal disease; tetany.
Creatinine: Renal disease.
Globulin: Globulin concentration will increase with dehydration and should also increase with antigenic stimulation.

Glucose: Diabetes, hyperglycemia, hypoglycemia, diabetes and liver disease.

Phosphorus: Kidney disease, hypoparathyroidism and nutritional disorders.

Potassium: Malnutrition and renal disease. This electrolyte is used to diagnose the causes of vomiting, diarrhea and cardiac symptoms.

Sodium: Dehydration, and diabetes. This electrolyte is used to diagnose the causes of vomiting, diarrhea and cardiac symptoms.

Total bilirubin: Hepatic disorders.

Total protein: Dehydration, kidney, liver disease, metabolic and nutritional disorders.

Blood Urea Nitrogen: Liver and kidney diseases.